What is intestinal metaplasia in the antrum?

What is intestinal metaplasia in the antrum?

What is intestinal metaplasia? Intestinal metaplasia is a transformation of the cells in the lining of your upper digestive tract, often the stomach or the esophagus (food pipe). It’s called “intestinal” metaplasia because the cells change to become more like those that line the intestines.

What is intestinal metaplasia with goblet cells?

Goblet cells normally line the intestines, not the esophagus. When goblet cells are found in a place where they are not supposed to be, like the lining of the esophagus, it is called intestinal metaplasia. Intestinal metaplasia can develop any place where squamous mucosa is normally found.

Is goblet cell metaplasia cancer?

The appearance of goblet cells in gastric epithelium is an indicator of potential malignant progression toward adenocarcinoma. Therefore, in vivo three-dimensional imaging of goblet cells is essential for diagnoses of a premalignant stage of gastric cancers called intestinal metaplasia.

What percentage of intestinal metaplasia becomes cancer?

In a retrospective study in Slovenia on cancer registry, the cumulative incidences of gastric cancer in those patients previously diagnosed with IM were 1.3% in complete IM-type I, 2.8% in incomplete IM-type II and 9.8% in incomplete IM-type III patients[53].

What is the best treatment for intestinal metaplasia?

There is no treatment for GIM. GIM is asymptomatic. Time to develop cancer has been reported to be 4.6–7 years.23, 29, 30 A European guideline in 2019 recommends regular surveillance for early cancer as the main management for GIM. In Asia, screening for early gastric cancer remains a prevalent approach.

Is intestinal metaplasia serious?

Intestinal metaplasia can be severe. The transformation of the cells of the gastric lining puts a person at a much higher risk of developing gastric cancer. While it is not possible to avoid some risk factors such as genetics, people can avoid other risk factors, including diet, H. pylori infection, and smoking.

How do you get rid of intestinal metaplasia?

After confirming a diagnosis of intestinal metaplasia, the doctor can begin treatment. Currently, the most effective treatment is to remove the H. pylori infection completely. This removal is done in combination with the use of antioxidant agents.

How long does it take for intestinal metaplasia to turn into cancer?

GIM is asymptomatic. Time to develop cancer has been reported to be 4.6–7 years.23, 29, 30 A European guideline in 2019 recommends regular surveillance for early cancer as the main management for GIM. In Asia, screening for early gastric cancer remains a prevalent approach.

How often does intestinal metaplasia turn into cancer?

Atrophic gastritis, intestinal metaplasia, mild-moderate dysplasia, and severe dysplasia were associated with annual incidences of gastric cancer of 0.1%, 0.25%, 0.6%, and 6.0%, respectively.

Does intestinal metaplasia mean cancer?

Intestinal metaplasia, a condition in which the cells lining the stomach are abnormal and may be a sign that you are at risk for developing cancer; however, it does not necessarily mean that you have cancer. 6 You may also have intestinal metaplasia without ever developing stomach cancer.

Can intestinal metaplasia be cured?

What foods should I avoid with intestinal metaplasia?

People who have gastrointestinal disorders such as GERD may find relief by avoiding fried, greasy, or spicy foods. Cutting out these foods may help reduce the inflammation that could be damaging the stomach. Salty foods may also be a culprit for intestinal metaplasia.

Is intestinal metaplasia curable?

In the long term, with follow up of at least five years, there is epidemiological evidence that IM may be reversible although a combination of antioxidant agents and eradication of H pylori may be necessary to achieve this.

What should I eat if I have metaplasia?

This typically includes eating a diet rich in whole, natural foods, such as vegetables, fruits, nuts, and whole grains. These foods contain more nutrients and antioxidants than processed foods, which may be helpful for risk factors of intestinal metaplasia.