Is iohexol a nonionic?

Is iohexol a nonionic?

Abstract. Iohexol and iopamidol are new second-generation nonionic contrast media.

Is Conray low osmolar?

Conray has an osmolarity of approximately 1000 mOsmol per liter, an osmolality of approximately 1400 mOsmol per kilogram and is, therefore, hypertonic under conditions of use. The viscosity (cps) is approximately 6 at 25°C and 4 at 37°C.

Is omnipaque 140 low osmolar?

OMNIPAQUE 140, OMNIPAQUE 180, OMNIPAQUE 240, OMNIPAQUE 300, and OMNIPAQUE 350 have osmolalities from approximately 1.1 to 3.0 times that of plasma (285 mOsm/kg water) or cerebrospinal fluid (301 mOsm/kg water) as shown in the above table and are hypertonic under conditions of use.

Is optiray water soluble?

Pharmacotherapeutic group: Water soluble, nephrotropic, low osmolar X-ray contrast media ATC code: V08AB07 Optiray 300 is a non-ionic X-ray contrast medium.

What is nonionic contrast used for?

What are Non-ionic iodinated contrast media? Iodinated contrast media is a contrast media containing iodine that is used in radiography to increase the clarity of the image.

What is nonionic contrast?

The non-ionic isotonic contrast agents represent a new class of intravascular iodinated x-ray contrast agents. They are highly hydrophilic, resulting in low chemotoxicity, are non-ionic, thereby eliminating Coulomb interactions, and are formulated in solutions iso-osmolar with the respective body fluids.

Is iohexol high or low osmolar?

The osmolality of iohexol ranges from 322 mOsm/kg—approximately 1.1 times that of blood plasma—to 844 mOsm/kg, almost three times that of blood. Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate, may be more than twice as high.

What is Conray contrast?

For more information about Cysto-Conray® II, please see the Full Prescribing Information. Cysto-Conray® II is an injectable, ionic, and high osmolar contrast agent intended for instillation into the urinary system. Provides a clear evaluation of the bladder and urinary tract1.

Is Omnipaque 140 high or low contrast?

IFU (PDF) Contrast Agent Aorta
Omnipaque 140 Iohexol
Omnipaque 180 Iohexol
Omnipaque 240 Iohexol
Omnipaque 300 Iohexol 50-80 ml

What kind of contrast is optiray?

Optiray 350 is a radiopaque (RAY dee oh payk) contrast agent. This medicine contains iodine, a substance that absorbs x-rays. Contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

What is ioversol used for?

Ioversol injection is used to help diagnose or find problems in the brain, heart, head, blood vessels, and other parts of the body. It is an iodinated contrast agent. Contrast agents are used to create a clear picture of the different parts of the body during certain medical procedures such as CT scans and angiography.

Which is better ionic and non-ionic contrast?

Ionic contrast media are less expensive but are associated with a higher incidence of adverse reactions than nonionic contrast agents; approximately 4 to 12 percent of patients receiving ionic media experience some hypersensitivity reaction within minutes or after several hours compared with 1 to 3 percent of patients …

What is iohexol used for?

Descriptions. Iohexol injection is used to help diagnose or find problems in the brain, back, heart, head, blood vessels, stomach, joints, pancreas, bladder, reproductive tract, and other parts of the body. It is an iodinated contrast agent.

What is the difference between high and low osmolar contrast?

The structure of iodinated contrast media. High-osmolality contrast media (HOCM) have an iodine to molecule ratio of 1.5 : 1. Low-osmolality, nonionic contrast media (LOCM) have an iodine to molecule ratio of 3 : 1. Isosmolar (isoosmolality) contrast media (IOCM) have an iodine to molecule ratio of 6 : 1.

What does Conray mean?

Conray is a sterile aqueous solution intended for use as a diagnostic radiopaque medium.

What is Conray 43 used for?

Conray 43 (iothalamate meglumine injection 43%) is a diagnostic radiopaque medium indicated for use in lower extremity venography, intravenous infusion urography, contrast enhancement of computed tomographic brain images and arterial digital subtraction angiography.

Is optiray low osmolar?

The intravenous clinical trial program of ioversol (Optiray), a low osmolar, nonionic, monomeric contrast agent characterized by high hydrophilicity, is evaluated on the basis of results from the first clinical trials conducted in Europe as part of the development of the 300 and 350 mgI/ml formulations: 7 double-blind.

What is optiray contrast?

Why is iodine used in contrast?

Iodine has a particular advantage as a contrast agent because the k-shell binding energy (k-edge) is 33.2 keV, similar to the average energy of x-rays used in diagnostic radiography 1. When the incident x-ray energy is closer to the k-edge of the atom it encounters, photoelectric absorption is more likely to occur.