Can UPJ obstruction cause high blood pressure?

Can UPJ obstruction cause high blood pressure?

In summary, unilateral UPJ obstruction is a cause of hypertension and can be related to the development of chronic kidney disease. Complications from paediatric UPJ obstruction can be prevented with early surgical evaluation, if indicated, but surgical repair can fail.

Can kidney obstruction cause high blood pressure?

Acute, unilateral obstruction can cause hypertension via activation of the renin-angiotensin system; renal vein renin studies lateralize the increase in renin secretion to the obstructed kidney, a finding similar to that in unilateral renal artery stenosis.

Can hydronephrosis cause high blood pressure?

Hydronephrosis is a common cause of acute kidney injury. Less frequently, it may lead to hypertension. Proposed factors include vasoconstriction and salt and water overload, mediated by processes including tubuloglomerular feedback (TGF) and the renin-angiotensin-aldosterone (RAA) axis.

What causes a PUJ obstruction?

Most commonly PUJ obstruction is caused by a congenital weakness in the wall of the junction. Sometimes there is an extra blood vessel pressing on the junction from outside causing or contributing to the obstruction (known as accessory vessel).

Can hydronephrosis cause hypotension?

Unilateral hydronephrosis appears to be sufficient to cause elevation of blood pressure, regardless of the presence of a normal contralateral kidney (3. Hypertension and unilateral hydronephrosis. J Urol. 1984;132:746–8.

Can a kidney stone cause high blood pressure?

Having crystals in your kidneys, and being prone to repeated obstruction from stones, virtually all stone formers might best consider themselves as having CKD even if glomerular filtration is not reduced. Stone formers are at increased risk for both high blood pressure and overt kidney disease.

How do kidneys affect blood pressure?

The kidneys help to control blood pressure by removing water and salt from the blood, as well as producing hormones that are involved in controlling blood pressure.

Can kidney infection cause high blood pressure?

If left untreated, a kidney infection can lead to potentially serious complications, such as: Kidney scarring. This can lead to chronic kidney disease, high blood pressure and kidney failure.

Can a kidney infection cause high blood pressure?

Is PUJ obstruction kidney disease?

The urine is pooled at the UPJ, and then flows down the ureters to the bladder. In UPJ obstruction, the flow of urine is slowed or stopped completely. This raises the risk of kidney damage. In most cases of UPJ obstruction, only one of the kidneys is affected.

Is PUJ obstruction curable?

Treatment. Most cases of UPJ obstruction actually do not require surgery and resolve on their own. However, if patients exhibit pain, recurrent infections, evidence of worsening function or increasing swelling, they may require a surgery called a pyeloplasty to prevent kidney injury and correct the blockage.

Can hydronephrosis cause hyperkalemia?

Serum chemistry studies can reveal an elevation of blood urea nitrogen (BUN) and creatinine levels, which may be the result of bilateral hydronephrosis and hydroureter. In addition, hyperkalemia can be a life-threatening condition.

How does obstructive uropathy cause hypertension?

Hypertension can occur in obstructive uropathy due to volume expansion and activation of the renin–angiotensin–aldosterone system. …

What creates high BP?

What causes high blood pressure? High blood pressure usually develops over time. It can happen because of unhealthy lifestyle choices, such as not getting enough regular physical activity. Certain health conditions, such as diabetes and having obesity, can also increase the risk for developing high blood pressure.

Do kidneys control BP?

The kidney plays a central role in the regulation of arterial blood pressure. A large body of experimental and physiological evidence indicates that renal control of extracellular volume and renal perfusion pressure are closely involved in maintaining the arterial circulation and blood pressure.

Is PUJ obstruction serious?

Because the obstruction is affected by blood flow the problem might stop and start, depending on how much blood is going through the vessel. PUJ obstruction can cause pain, repeated urine infections and damage to the affected kidney, but often there are no symptoms at all.

What are the symptoms of PUJ obstruction?


  • Back or flank pain.
  • Bloody urine (hematuria)
  • Lump in the abdomen (abdominal mass)
  • Kidney infection.
  • Poor growth in infants (failure to thrive)
  • Urinary tract infection, usually with fever.
  • Vomiting.

What are 3 causes of hyperkalemia?

What causes hyperkalemia?

  • Kidney Disease. Hyperkalemia can happen if your kidneys do not work well.
  • A diet high in potassium. Eating too much food that is high in potassium can also cause hyperkalemia, especially in people with advanced kidney disease.
  • Drugs that prevent the kidneys from losing enough potassium.

Does kidney stone cause high blood pressure?