What is MDA MB 453 cell line?
What is MDA MB 453 cell line?
The MDA-MB-453 cell line is androgen receptor-positive and ‘triple-negative’ in respect to estrogen receptor-α, progesterone receptor and the Her-2/neu protein expression.
What is MDA cell line?
The MDA-MB-231 cell line is an epithelial, human breast cancer cell line that was established from a pleural effusion of a 51-year-old caucasian female with a metastatic mammary adenocarcinoma1 and is one of the most commonly used breast cancer cell lines in medical research laboratories.
What is bt474 cell line?
BT-474 is a cell line exhibiting epithelial morphology that was isolated from a solid, invasive ductal carcinoma of the breast obtained from a 60-year-old, White, female breast cancer patient. Use these cells in your cancer research.
What are HMEC cells?
Lonza’s Human Mammary Epithelial Cells (HMEC) are isolated from adult female breast tissue. The cells have been primarily utilized to understand the formation of breast cancer.
Does MCF 7 express HER2?
MCF7-HER2 cells, treated with an inhibitor of protein synthesis cycloheximide show a slower decrease in survivin protein level in HER-2 over-expressing MCF7 cells than in control cells (data not shown), which suggests that up-regulation of survivin is post translational.
How is a cancerous is different from normal cell?
How is a cancerous cell different from a normal cell?…
Cancer cells | Normal cells |
---|---|
i. Divide in an uncontrolled manner. | i. Divide in a regulated manner. |
ii. Do not show contact inhibition. | ii. Show contact inhibition. |
Why do we need to determine which cell lines?
Why do we need to determine which cell lines produced the highest recombinant FIX? To reduce the cost of hemophilia treatment. The cell lines produce recombinant FIX and other proteins.
What are HMEC 1 cells?
HMEC-1 specifically bind lymphocytes in cell adhesion assays. Thus HMEC-1 is the first immortalized human microvascular endothelial cell line that retains the morphologic, phenotypic, and functional characteristics of normal human microvascular endothelial cells.